

| 货号 | HA778014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human PSG9 Polyclonal Antibody (HA778014) is a rabbit polyclonal antibody detecting Pregnancy-specific beta-1-glycoprotein 9; PS-beta-G-9; PSBG-9; Pregnancy-specific glycoprotein 9; PS34; Pregnancy-specific beta-1 glycoprotein B; PS-beta-B; Pregnancy-specific beta-1-glycoprotein 11; PS-beta-G-11; PSBG-11; Pregnancy-specific glycoprotein 11; Pregnancy-specific glycoprotein 7; PSG7; PSG9; PSG11 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human PSG9 (Glu35-Ser426). | ||||||||
| 靶标 | Pregnancy-specific beta-1-glycoprotein 9; PS-beta-G-9; PSBG-9; Pregnancy-specific glycoprotein 9; PS34; Pregnancy-specific beta-1 glycoprotein B; PS-beta-B; Pregnancy-specific beta-1-glycoprotein 11; PS-beta-G-11; PSBG-11; Pregnancy-specific glycoprotein 11; Pregnancy-specific glycoprotein 7; PSG7; PSG9; PSG11 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q00887, Q00889, Q16557, Q13046, Q00888, Q9UQ74 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Pregnancy-specific beta-1-glycoprotein 9 (PSG9) is a ~48 kDa protein. Binds to the small latent transforming growth factor-beta complex, consisting of the N-terminal TGFB1 latency-associated peptide (LAP) and the mature form of TGFB1, thereby leading to the activation of TGFB1. The activation of TGFB1 leads to stimulation of naive CD4(+) T-cells to increase FoxP3 expression and to an increase in the number of FoxP3(+) regulatory T-cells. Induces the differentiation of a suppressive CD4(+)LAP(+)FoxP3(-) T-cell subset. Induces the secretion of TGFB1 in macrophages, but not in activated CD4(+) T-cells. May reduce the expression of several pro-inflammatory cytokines and chemokines by CD4(+) T-cells, including IL2 and IL6. 1. Jones, K. et al. (2016) PloS one 11, e0158050. PMID: 27389696 | ||||||||
| Note | For research use only |

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