Anti-MTA1 Polyclonal Antibody (HA784014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HA784014

品牌

abinScience

描述

Anti-MTA1 Polyclonal Antibody (HA784014) is a rabbit polyclonal antibody detecting Metastasis-associated protein MTA1; MTA1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human MTA1 (Met1-Leu430).

靶标

Metastasis-associated protein MTA1; MTA1

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q13330, Q8K4B0, Q62599

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Metastasis-associated protein MTA1 is a ~80 kDa protein. Transcriptional coregulator which can act as both a transcriptional corepressor and coactivator. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. In the NuRD complex, regulates transcription of its targets by modifying the acetylation status of the target chromatin and cofactor accessibility to the target DNA. In conjunction with other components of NuRD, acts as a transcriptional corepressor of BRCA1, ESR1, TFF1 and CDKN1A. Acts as a transcriptional coactivator of BCAS3, and SUMO2, independent of the NuRD complex.

1. Gururaj, AE. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 6670-5. PMID: 16617102

2. Balasenthil, S. et al. (2007) Cancer research 67, 7132-8. PMID: 17671180

3. Molli, PR. et al. (2008) Oncogene 27, 1971-80. PMID: 17922032

4. Cong, L. et al. (2011) The Journal of biological chemistry 286, 43793-43808. PMID: 21965678

5. Kang, HJ. et al. (2014) Cancer research 74, 1484-94. PMID: 24413532

6. Le Guezennec, X. et al. (2006) Molecular and cellular biology 26, 843-51. PMID: 16428440

7. Hoffmeister, H. et al. (2017) Nucleic acids research 45, 10534-10554. PMID: 28977666

8. Li, DQ. et al. (2009) The Journal of biological chemistry 284, 34545-52. PMID: 19837670

Note

For research use only

图片

参考文献

产品说明书

Anti-MTA1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-MTA1 Polyclonal Antibody (HA784014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-MTA1 Polyclonal Antibody (HA784014)

概述

图片

参考文献

产品说明书

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