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Anti-P2RX1 Polyclonal Antibody (HA787014)

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概述
货号HA787014
品牌abinScience
描述
Anti-P2RX1 Polyclonal Antibody (HA787014) is a rabbit polyclonal antibody detecting P2X purinoceptor 1; P2X1; ATP receptor; Purinergic receptor; P2RX1; P2X1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant human P2RX1 (Gln56-Asp327).
靶标P2X purinoceptor 1; P2X1; ATP receptor; Purinergic receptor; P2RX1; P2X1
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号P51575, P51576, P47824
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

P2X purinoceptor 1 (P2RX1) is a ~44 kDa protein. ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and with relatively high calcium permeability. Furthermore, CTP functions as a weak affinity agonist for P2RX1. Plays a role a role in urogenital, immune and cardiovascular function. Specifically, plays an important role in neurogenic contraction of smooth muscle of the vas deferens, and therefore is essential for normal male reproductive function. In addition, contributes to smooth muscle contractions of the urinary bladder.

1. Bianchi, BR. et al. (1999) European journal of pharmacology 376, 127-38. PMID: 10440098
2. Egan, TM. et al. (2004) The Journal of neuroscience : the official journal of the Society for Neuroscience 24, 3413-20. PMID: 15056721
3. Allsopp, RC. et al. (2010) The Journal of biological chemistry 285, 32770-32777. PMID: 20699225
4. Valera, S. et al. (1995) Receptors & channels 3, 283-9. PMID: 8834001
5. Evans, RJ. et al. (1996) The Journal of physiology 497 ( Pt 2), 413-22. PMID: 8961184
6. Roberts, JA. et al. (2004) The Journal of biological chemistry 279, 9043-55. PMID: 14699168
7. Lecut, C. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 183, 2801-9. PMID: 19635923
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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