

| 货号 | HA797014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-SLBP Polyclonal Antibody (HA797014) is a rabbit polyclonal antibody detecting Histone RNA hairpin-binding protein; Histone stem-loop-binding protein; SLBP; HBP in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human SLBP (Cys72-Asp198). | ||||||||
| 靶标 | Histone RNA hairpin-binding protein; Histone stem-loop-binding protein; SLBP; HBP | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q14493, P97440 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Histone RNA hairpin-binding protein (SLBP) is a ~31 kDa protein. RNA-binding protein involved in the histone pre-mRNA processing. Binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3'-end processing by stabilizing the complex between histone pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP), via the histone downstream element (HDE). Plays an important role in targeting mature histone mRNA from the nucleus to the cytoplasm and to the translation machinery. Stabilizes mature histone mRNA and could be involved in cell-cycle regulation of histone gene expression. Involved in the mechanism by which growing oocytes accumulate histone proteins that support early embryogenesis. 1. Zheng, L. et al. (2003) Molecular and cellular biology 23, 1590-601. PMID: 12588979 2. Sullivan, KD. et al. (2009) RNA (New York, N.Y.) 15, 459-72. PMID: 19155325 3. Wang, ZF. et al. (1996) Genes & development 10, 3028-40. PMID: 8957003 4. Martin, F. et al. (1997) The EMBO journal 16, 769-78. PMID: 9049306 | ||||||||
| Note | For research use only |

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