Anti-CHRNA2 Polyclonal Antibody (HA818014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HA818014

品牌

abinScience

描述

Anti-CHRNA2 Polyclonal Antibody (HA818014) is a rabbit polyclonal antibody detecting Neuronal acetylcholine receptor subunit alpha-2; CHRNA2 in ELISA, IHC, WB. Suitable for Human, Rat, Mouse, and Chicken.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human CHRNA2 (Glu27-Pro265).

靶标

Neuronal acetylcholine receptor subunit alpha-2; CHRNA2

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q15822, P12389, Q91X60, P09480

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Neuronal acetylcholine receptor subunit alpha-2 (CHRNA2) is a ~59 kDa protein. Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collection of nAChR subunits known to mediate synaptic transmission in the nervous system and the neuromuscular junction. Each nAchR subunit confers differential attributes to channel properties, including activation, deactivation and desensitization kinetics, pH sensitivity, cation permeability, and binding to allosteric modulators. CHRNA2 forms heteropentameric neuronal acetylcholine receptors with CHRNB2 and CHRNB4 and plays a role in nicotine dependence.

1. Millar, NS. et al. (2009) Neuropharmacology 56, 237-46. PMID: 18723036

2. Dash, B. et al. (2014) Neuropharmacology 79, 715-25. PMID: 24467848

3. Kouvatsos, N. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 9635-40. PMID: 27493220

Note

For research use only

图片

参考文献

产品说明书

Anti-CHRNA2 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CHRNA2 Polyclonal Antibody (HA818014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CHRNA2 Polyclonal Antibody (HA818014)

概述

图片

参考文献

产品说明书

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