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Anti-ABCC10 Polyclonal Antibody (HB315014)

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概述
货号HB315014
品牌abinScience
描述
Anti-ABCC10 Polyclonal Antibody (HB315014) is a rabbit polyclonal antibody detecting ATP-binding cassette sub-family C member 10; 7.6.2.2; 7.6.2.3; Multidrug resistance-associated protein 7; ABCC10; MRP7; SIMRP7 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant human ABCC10 (Leu1225-Pro1492).
靶标ATP-binding cassette sub-family C member 10; 7.6.2.2; 7.6.2.3; Multidrug resistance-associated protein 7; ABCC10; MRP7; SIMRP7
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q5T3U5, Q8R4P9
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

ATP-binding cassette sub-family C member 10 (ABCC10) is a ~161 kDa protein. ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Lipophilic anion transporter that mediates ATP-dependent transport of glucuronide conjugates such as estradiol-17-beta-o-glucuronide and GSH conjugates such as leukotriene C4 (LTC4). May regulate the transport of organic compounds in testes across the blood-testis-barrier (Probable). Mediates intercellular propagation of antiviral immune signaling in early stages of infection. In RNA virus-infected cells, oligoadenylate synthase senses viral dsRNA and generates 2',5'-oligoadenylates (2-5A) which act as second messengers to activate RNASEL and type I interferon signaling to inhibit viral replication.

1. Chen, ZS. et al. (2003) Molecular pharmacology 63, 351-8. PMID: 12527806
2. Hopper-Borge, E. et al. (2004) Cancer research 64, 4927-30. PMID: 15256465
3. Malofeeva, EV. et al. (2012) Cancer research 72, 6457-67. PMID: 23087055
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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