

| 货号 | HB315014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-ABCC10 Polyclonal Antibody (HB315014) is a rabbit polyclonal antibody detecting ATP-binding cassette sub-family C member 10; 7.6.2.2; 7.6.2.3; Multidrug resistance-associated protein 7; ABCC10; MRP7; SIMRP7 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human ABCC10 (Leu1225-Pro1492). | ||||||||
| 靶标 | ATP-binding cassette sub-family C member 10; 7.6.2.2; 7.6.2.3; Multidrug resistance-associated protein 7; ABCC10; MRP7; SIMRP7 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q5T3U5, Q8R4P9 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | ATP-binding cassette sub-family C member 10 (ABCC10) is a ~161 kDa protein. ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds, and xenobiotics from cells. Lipophilic anion transporter that mediates ATP-dependent transport of glucuronide conjugates such as estradiol-17-beta-o-glucuronide and GSH conjugates such as leukotriene C4 (LTC4). May regulate the transport of organic compounds in testes across the blood-testis-barrier (Probable). Mediates intercellular propagation of antiviral immune signaling in early stages of infection. In RNA virus-infected cells, oligoadenylate synthase senses viral dsRNA and generates 2',5'-oligoadenylates (2-5A) which act as second messengers to activate RNASEL and type I interferon signaling to inhibit viral replication. 1. Chen, ZS. et al. (2003) Molecular pharmacology 63, 351-8. PMID: 12527806 2. Hopper-Borge, E. et al. (2004) Cancer research 64, 4927-30. PMID: 15256465 3. Malofeeva, EV. et al. (2012) Cancer research 72, 6457-67. PMID: 23087055 | ||||||||
| Note | For research use only |

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