Anti-SMARCD3 Polyclonal Antibody (HB357014)

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50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HB357014

品牌

abinScience

描述

Anti-SMARCD3 Polyclonal Antibody (HB357014) is a rabbit polyclonal antibody detecting SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3; 60 kDa BRG-1/Brm-associated factor subunit C; BRG1-associated factor 60C; BAF60C; SMARCD3; BAF60C in ELISA, IHC, WB. Suitable for Mouse and Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human SMARCD3 (Arg149-Pro367).

靶标

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3; 60 kDa BRG-1/Brm-associated factor subunit C; BRG1-associated factor 60C; BAF60C; SMARCD3; BAF60C

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q6P9Z1, Q6STE5

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 (SMARCD3) is a ~54 kDa protein. Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Stimulates nuclear receptor mediated transcription. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state.

1. Euskirchen, G. et al. (2012) The Journal of biological chemistry 287, 30897-905. PMID: 22952240

2. Kadoch, C. et al. (2015) Science advances 1, e1500447. PMID: 26601204

3. Lessard, J. et al. (2007) Neuron 55, 201-15. PMID: 17640523

Note

For research use only

图片

Western blot

Western blot analysis was performed using anti-SMARCD3 polyclonal antibody at 1ug/mL on various samples.
Lane 1: BxPC-3 cell lysate
Lane 2: Hela cell lysate
Lane 3: U87 cell lysate
Lane 4: 293T cell lysate
Lane 5: K562 cell lysate
Lane 6: Jurkat cell lysate

参考文献

产品说明书

Anti-SMARCD3 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

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Anti-SMARCD3 Polyclonal Antibody (HB357014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-SMARCD3 Polyclonal Antibody (HB357014)

概述

图片

参考文献

产品说明书

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