Anti-ATF7IP Polyclonal Antibody (HB362014)

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规格：

50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HB362014

品牌

abinScience

描述

Anti-ATF7IP Polyclonal Antibody (HB362014) is a rabbit polyclonal antibody detecting Activating transcription factor 7-interacting protein 1; ATF-interacting protein; ATF-IP; ATF7-interacting protein; ATFa-associated modulator; hAM; MBD1-containing chromatin-associated factor 1; P621; ATF7IP; MCAF; MCAF1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Chicken.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human ATF7IP (Gln1149-Ser1270).

靶标

Activating transcription factor 7-interacting protein 1; ATF-interacting protein; ATF-IP; ATF7-interacting protein; ATFa-associated modulator; hAM; MBD1-containing chromatin-associated factor 1; P621; ATF7IP; MCAF; MCAF1

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q6VMQ6, Q7TT18, Q5ZIE8

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Activating transcription factor 7-interacting protein 1 (ATF7IP) is a ~136 kDa protein. Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Required for HUSH-mediated heterochromatin formation and gene silencing. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Stabilizes SETDB1, is required to stimulate histone methyltransferase activity of SETDB1 and facilitates the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3).

1. Timms, RT. et al. (2016) Cell reports 17, 653-659. PMID: 27732843

2. Fujita, N. et al. (2003) Molecular and cellular biology 23, 2834-43. PMID: 12665582

3. Wang, H. et al. (2003) Molecular cell 12, 475-87. PMID: 14536086

4. Liu, L. et al. (2009) The Journal of biological chemistry 284, 5165-74. PMID: 19106100

Note

For research use only

图片

参考文献

产品说明书

Anti-ATF7IP Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ATF7IP Polyclonal Antibody (HB362014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-ATF7IP Polyclonal Antibody (HB362014)

概述

图片

参考文献

产品说明书

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