Anti-Human SLC30A10 Polyclonal Antibody (HB363014)

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概述
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概述

货号

HB363014

品牌

abinScience

描述

Anti-Human SLC30A10 Polyclonal Antibody (HB363014) is a rabbit polyclonal antibody detecting Calcium/manganese antiporter SLC30A10; Solute carrier family 30 member 10; Zinc transporter 10; ZnT-10; SLC30A10; ZNT10; ZNT8 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human SLC30A10 (Lys300-Gly427).

靶标

Calcium/manganese antiporter SLC30A10; Solute carrier family 30 member 10; Zinc transporter 10; ZnT-10; SLC30A10; ZNT10; ZNT8

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q6XR72

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Calcium/manganese antiporter SLC30A10 is a ~52 kDa protein. Calcium:manganese antiporter of the plasma membrane mediating the efflux of intracellular manganese coupled to an active extracellular calcium exchange. Required for intracellular manganese homeostasis, an essential cation for the function of several enzymes, including some crucially important for the metabolism of neurotransmitters and other neuronal metabolic pathways. Manganese can also be cytotoxic and induce oxidative stress, mitochondrial dysfunction and apoptosis. Could also have an intracellular zinc ion transporter activity, directly regulating intracellular zinc ion homeostasis and more indirectly various signaling pathway and biological processes.

1. Levy, M. et al. (2019) The Journal of biological chemistry 294, 5879-5889. PMID: 30755481

2. Tuschl, K. et al. (2012) American journal of human genetics 90, 457-66. PMID: 22341972

3. Leyva-Illades, D. et al. (2014) The Journal of neuroscience : the official journal of the Society for Neuroscience 34, 14079-95. PMID: 25319704

4. Zhao, Y. et al. (2016) Traffic (Copenhagen, Denmark) 17, 267-88. PMID: 26728129

5. Nishito, Y. et al. (2016) The Journal of biological chemistry 291, 14773-87. PMID: 27226609

6. Zogzas, CE. et al. (2016) The Journal of biological chemistry 291, 15940-57. PMID: 27307044

7. Patrushev, N. et al. (2012) PloS one 7, e33211. PMID: 22427991

Note

For research use only

图片

参考文献

产品说明书

Anti-Human SLC30A10 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SLC30A10 Polyclonal Antibody (HB363014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SLC30A10 Polyclonal Antibody (HB363014)

概述

图片

参考文献

产品说明书

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