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Anti-Human PADI6 Polyclonal Antibody (HB365014)

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概述
货号HB365014
品牌abinScience
描述
Anti-Human PADI6 Polyclonal Antibody (HB365014) is a rabbit polyclonal antibody detecting Protein-arginine deiminase type-6; 3.5.3.15; Peptidyl arginine deiminase-like protein; Peptidylarginine deiminase VI; hPADVI; Protein-arginine deiminase type VI; PADI6; PAD6 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant human PADI6 (Val2-Pro694).
靶标Protein-arginine deiminase type-6; 3.5.3.15; Peptidyl arginine deiminase-like protein; Peptidylarginine deiminase VI; hPADVI; Protein-arginine deiminase type VI; PADI6; PAD6
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q6TGC4
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Inactive protein-arginine deiminase type-6 (PADI6) is a ~77 kDa protein. Structural constituent of cytoplasmic lattices, which plays a key role in early embryonic development. Cytoplasmic lattices consist in fibrous structures found in the cytoplasm of oocytes and preimplantation embryos. They are required to store maternal proteins critical for embryonic development, such as ribosomal proteins and proteins that control epigenetic reprogramming of the preimplantation embryo, and prevent their degradation or activation. In contrast to other members of the family, does not show protein-arginine deiminase activity due to its inability to bind Ca(2+).

1. Jentoft, IMA. et al. (2023) Cell 186, 5308-5327.e25. PMID: 37922900
2. Ranaivoson, FM. et al. (2024) IUCrJ 11, 395-404. PMID: 38656308
3. Williams, JPC. et al. (2024) Computational and structural biotechnology journal 23, 3258-3269. PMID: 39286527
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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