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Anti-SLC7A10 Polyclonal Antibody (HC020014)

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概述
货号HC020014
品牌abinScience
描述
Anti-SLC7A10 Polyclonal Antibody (HC020014) is a rabbit polyclonal antibody detecting Asc-type amino acid transporter 1; Asc-1; Solute carrier family 7 member 10; SLC7A10; ASC1 in ELISA, IHC, WB. Suitable for Human, Rabbit, Rat, and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant human SLC7A10 (Ala2-Glu39&Met291-Gly312&Arg470-Gln523).
靶标Asc-type amino acid transporter 1; Asc-1; Solute carrier family 7 member 10; SLC7A10; ASC1
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q9NS82, Q9N1Q4, Q9WVR6, Q9QXW9, Q9UHI5
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Asc-type amino acid transporter 1 (SLC7A10) is a ~56 kDa protein. Associates with SLC3A2/4F2hc to form a functional heterodimeric complex that translocates small neutral L- and D-amino acids across the plasma membrane. Preferentially mediates exchange transport, but can also operate via facilitated diffusion. Acts as a major transporter for glycine, L- and D-serine in the central nervous system. At the spinal cord and brainstem regulates glycine metabolism and glycinergic inhibitory neurotransmission by providing for glycine de novo synthesis from L-serine and glycine recycling from astrocytes to glycinergic motor neurons. At Schaffer collateral-CA1 synapses mediates D-serine and glycine release that modulates post-synaptic activation of NMDA receptors and excitatory glutamatergic transmission.

1. Nakauchi, J. et al. (2000) Neuroscience letters 287, 231-5. PMID: 10863037
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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