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Anti-Human SLC29A1 Polyclonal Antibody (HA253014)

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  • 100ug
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概述
货号HA253014
品牌abinScience
描述
Anti-Human SLC29A1 Polyclonal Antibody (HA253014) is a rabbit polyclonal antibody detecting es-type; Solute carrier family 29 member 1; SLC29A1; ENT1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant human SLC29A1 (Asn30-Asn82&Arg228-Val291).
靶标Equilibrative nucleoside transporter 1; hENT1; Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter; Equilibrative NBMPR-sensitive nucleoside transporter; es nucleoside transporter; Nucleoside transporter, es-type; Solute carrier family 29 member 1; SLC29A1; ENT1
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q99808
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Equilibrative nucleoside transporter 1 (SLC29A1) is a ~50 kDa protein. Uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent transporter. Involved in the transport of nucleosides such as adenosine, guanosine, inosine, uridine, thymidine and cytidine. Also transports purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Mediates basolateral nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis barrier.

1. Ward, JL. et al. (2000) The Journal of biological chemistry 275, 8375-81. PMID: 10722669
2. Lum, PY. et al. (2000) Cancer chemotherapy and pharmacology 45, 273-8. PMID: 10755314
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4. Endres, CJ. et al. (2004) The Biochemical journal 380, 131-7. PMID: 14759222
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6. Visser, F. et al. (2007) The Journal of biological chemistry 282, 14148-57. PMID: 17379602
7. Yao, SY. et al. (2011) The Journal of biological chemistry 286, 32552-62. PMID: 21795683
8. Aseervatham, J. et al. (2015) PloS one 10, e0136779. PMID: 26406980
9. Huang, W. et al. (2017) Protein & cell 8, 284-295. PMID: 27995448
10. Niemann, B. et al. (2022) Nature 609, 361-368. PMID: 35790189
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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