Anti-Human SLC31A1 Polyclonal Antibody (HC035014)

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概述
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参考文献
产品说明书

概述

货号

HC035014

品牌

abinScience

描述

Anti-Human SLC31A1 Polyclonal Antibody (HC035014) is a rabbit polyclonal antibody detecting High affinity copper uptake protein 1; Copper transporter 1; hCTR1; Solute carrier family 31 member 1; Truncated CTR1 form; SLC31A1; COPT1; CTR1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human SLC31A1 (Asp2-Leu61&Tyr83-His132).

靶标

High affinity copper uptake protein 1; Copper transporter 1; hCTR1; Solute carrier family 31 member 1; Truncated CTR1 form; SLC31A1; COPT1; CTR1

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

O15431

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

High affinity copper uptake protein 1 (SLC31A1) is a ~21 kDa protein. Uniporter that mediates the transport of copper(1+) from the extracellular space to the cytoplasm, across the plasma membrane and delivers directly copper(1+) to specific chaperone such as ATOX1, via a copper(1+)- mediated transient interaction between the C-terminal domain and a copper(1+) chaperone, thus controlling intracellular copper(1+) levels. May function in copper(1+) import from the apical membrane thus may drive intestinal copper absorption. The copper(1+) transport mechanism is sodium-independent, saturable and of high-affinity. Also mediates the uptake of silver(1+). May function in the influx of the platinum-containing chemotherapeutic agents.

1. Lee, J. et al. (2002) The Journal of biological chemistry 277, 4380-7. PMID: 11734551

2. Eisses, JF. et al. (2005) The Journal of biological chemistry 280, 37159-68. PMID: 16135512

3. Maryon, EB. et al. (2007) The Journal of biological chemistry 282, 20376-87. PMID: 17525160

4. Molloy, SA. et al. (2009) The Journal of biological chemistry 284, 29704-13. PMID: 19740744

5. Larson, CA. et al. (2010) Biochemical pharmacology 80, 448-54. PMID: 20451502

6. Bertinato, J. et al. (2010) Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 24, 178-84. PMID: 20569931

7. Maryon, EB. et al. (2013) The Journal of biological chemistry 288, 18035-46. PMID: 23658018

Note

For research use only

图片

参考文献

产品说明书

Anti-Human SLC31A1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SLC31A1 Polyclonal Antibody (HC035014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SLC31A1 Polyclonal Antibody (HC035014)

概述

图片

参考文献

产品说明书

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