

| 货号 | HB411014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-UBXN2B Polyclonal Antibody (HB411014) is a rabbit polyclonal antibody detecting UBX domain-containing protein 2B; NSFL1 cofactor p37; p97 cofactor p37; UBXN2B in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.
Highlights
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| 种属反应性 | Human | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human UBXN2B (Leu244-Lys331). | ||||||||
| 靶标 | UBX domain-containing protein 2B; NSFL1 cofactor p37; p97 cofactor p37; UBXN2B | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q14CS0, P0C627, Q0KL01 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | UBX domain-containing protein 2B (UBXN2B) is a ~37 kDa protein. Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase. 1. Uchiyama, K. et al. (2006) Developmental cell 11, 803-16. PMID: 17141156 2. Kress, E. et al. (2013) The Journal of cell biology 201, 559-75. PMID: 23649807 | ||||||||
| Note | For research use only |

Lane 1: A549 cell lysate



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