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Anti-UBAP2L Polyclonal Antibody (HC057014)

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概述
货号HC057014
品牌abinScience
描述
Anti-UBAP2L Polyclonal Antibody (HC057014) is a rabbit polyclonal antibody detecting Ubiquitin-associated protein 2-like; Protein NICE-4; RNA polymerase II degradation factor UBAP2L; UBAP2L; KIAA0144; NICE4 in ELISA, IHC, WB. Suitable for Mouse and Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Human, Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant human UBAP2L (Gln30-Trp96).
靶标Ubiquitin-associated protein 2-like; Protein NICE-4; RNA polymerase II degradation factor UBAP2L; UBAP2L; KIAA0144; NICE4
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q80X50, Q14157
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Ubiquitin-associated protein 2-like (UBAP2L) is a ~116 kDa protein. Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled nucleotide excision repair (TC-NER) machinery fails to resolve DNA damage. Plays an important role in the activity of long-term repopulating hematopoietic stem cells (LT-HSCs). Is a regulator of stress granule assembly, required for their efficient formation. Required for proper brain development and neocortex lamination.

1. Bordeleau, ME. et al. (2014) Blood 124, 2362-9. PMID: 25185265
2. Jia, X. et al. (2022) Science advances 8, eabo7112. PMID: 35977029
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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