

| 货号 | HB435014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-SLC4A10 Polyclonal Antibody (HB435014) is a rabbit polyclonal antibody detecting Sodium-driven chloride bicarbonate exchanger; Solute carrier family 4 member 10; SLC4A10; NBCN2; NCBE in ELISA, IHC, WB. Suitable for Human, Bovine, Rat, and Mouse.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human SLC4A10 (Asp93-Trp432). | ||||||||
| 靶标 | Sodium-driven chloride bicarbonate exchanger; Solute carrier family 4 member 10; SLC4A10; NBCN2; NCBE | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q6U841, Q32LP4, Q80ZA5, Q5DTL9 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Sodium-driven chloride bicarbonate exchanger (SLC4A10) is a ~125 kDa protein. Sodium/bicarbonate cotransporter which plays an important role in regulating intracellular pH. Has been shown to act as a sodium/bicarbonate cotransporter in exchange for intracellular chloride. Has also been shown to act as a sodium/biocarbonate cotransporter which does not couple net influx of bicarbonate to net efflux of chloride, with the observed chloride efflux being due to chloride self-exchange. Controls neuronal pH and may contribute to the secretion of cerebrospinal fluid. Acting on presynaptic intracellular pH, it promotes GABA release, reduces the excitability of CA1 pyramidal neurons, and modulates short-term synaptic plasticity. 1. Parker, MD. et al. (2008) The Journal of biological chemistry 283, 12777-88. PMID: 18319254 | ||||||||
| Note | For research use only |

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