Anti-IYD Polyclonal Antibody (HB478014)

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概述
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概述

货号

HB478014

品牌

abinScience

描述

Anti-IYD Polyclonal Antibody (HB478014) is a rabbit polyclonal antibody detecting Iodotyrosine deiodinase 1; IYD-1; 1.21.1.1; Iodotyrosine dehalogenase 1; IYD; C6orf71; DEHAL1 in ELISA, IHC, WB. Suitable for Human, Rat, Mouse, and Pig.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human IYD (Tyr81-Val289).

靶标

Iodotyrosine deiodinase 1; IYD-1; 1.21.1.1; Iodotyrosine dehalogenase 1; IYD; C6orf71; DEHAL1

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q6PHW0, Q5BK17, Q9DCX8, Q6TA49

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Iodotyrosine deiodinase 1 (IYD) is a ~33 kDa protein. Catalyzes the dehalogenation of halotyrosines such as 3-bromo-L-tyrosine, 3-chloro-L-tyrosine, 3-iodo-L-tyrosine and 3,5-diiodo-L-tyrosine. During thyroid hormone biosynthesis, facilitates iodide salvage by catalysing the oxidative NADPH-dependent deiodination of the halogenated by-products of thyroid hormone production, monoiodotyrosine (L-MIT) and diiodotyrosine (L-DIT). The scavanged iodide can then reenter the hormone-producing pathways. Acts more efficiently on 3-iodo-L-tyrosine than 3,5-diiodo-L-tyrosine.

1. Gnidehou, S. et al. (2004) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 18, 1574-6. PMID: 15289438

2. Moreno, JC. et al. (2008) The New England journal of medicine 358, 1811-8. PMID: 18434651

3. Hu, J. et al. (2015) The Journal of biological chemistry 290, 590-600. PMID: 25395621

4. Ingavat, N. et al. (2017) Biochemistry 56, 1130-1139. PMID: 28157283

Note

For research use only

图片

参考文献

产品说明书

Anti-IYD Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-IYD Polyclonal Antibody (HB478014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-IYD Polyclonal Antibody (HB478014)

概述

图片

参考文献

产品说明书

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