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Anti-GHITM Polyclonal Antibody (HB496014)

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概述
货号HB496014
品牌abinScience
描述
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant human GHITM (Leu2-Arg82).
靶标Growth hormone-inducible transmembrane protein; Dermal papilla-derived protein 2; Mitochondrial morphology and cristae structure 1; MICS1; Transmembrane BAX inhibitor motif-containing protein 5; GHITM; DERP2; MICS1; TMBIM5; My021; UNQ244/PRO281
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q9H3K2, Q91VC9, Q5XIA8
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Growth hormone-inducible transmembrane protein (GHITM) is a ~37 kDa protein. Plays an important role in maintenance of mitochondrial morphology and in mediating either calcium or potassium/proton antiport. Mediates proton-dependent calcium efflux from mitochondrion. Also functions as an electroneutral mitochondrial proton/potassium exchanger. Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c.

1. Oka, T. et al. (2008) Molecular biology of the cell 19, 2597-608. PMID: 18417609
2. Seitaj, B. et al. (2020) Cells 9. PMID: 32977469
3. Patron, M. et al. (2022) The EMBO journal 41, e110476. PMID: 35912435
4. Austin, S. et al. (2022) EMBO reports 23, e54978. PMID: 36321428
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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