

| 货号 | HB497014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-SMUG1 Polyclonal Antibody (HB497014) is a rabbit polyclonal antibody detecting Single-strand selective monofunctional uracil DNA glycosylase; 3.2.2.-; SMUG1 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Rat.
Highlights
| ||||||||
| 种属反应性 | Human, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human SMUG1 (Ser26-Lys270). | ||||||||
| 靶标 | Single-strand selective monofunctional uracil DNA glycosylase; 3.2.2.-; SMUG1 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q53HV7, Q6P5C5, Q59I47, Q811Q1 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||||
| 产品使用信息 |
| ||||||||
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Single-strand selective monofunctional uracil DNA glycosylase (SMUG1) is a ~29 kDa protein. Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine), nor other oxidized bases. The activity is damage-specific and salt-dependent. | ||||||||
| Note | For research use only |

24小时产品查询

扫一扫关注我们

专属渠道经理