

| 货号 | HB514014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-FOXE3 Polyclonal Antibody (HB514014) is a rabbit polyclonal antibody detecting Forkhead box protein E3; Forkhead-related protein FKHL12; Forkhead-related transcription factor 8; FREAC-8; FOXE3; FKHL12; FREAC8 in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human FOXE3 (Pro73-Leu161). | ||||||||
| 靶标 | Forkhead box protein E3; Forkhead-related protein FKHL12; Forkhead-related transcription factor 8; FREAC-8; FOXE3; FKHL12; FREAC8 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q13461, Q63250, Q9QY14 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Forkhead box protein E3 (FOXE3) is a ~33 kDa protein. Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle. During lens development, controls the ratio of the lens fiber cells to the cells of the anterior lens epithelium by regulating the rate of proliferation and differentiation. Controls lens vesicle closure and subsequent separation of the lens vesicle from ectoderm. Controls the expression of DNAJB1 in a pathway that is crucial for the development of the anterior segment of the eye. 1. Wang, Y. et al. (2012) Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 250, 999-1007. PMID: 22527307 2. Islam, L. et al. (2015) Human mutation 36, 296-300. PMID: 25504734 3. Khan, SY. et al. (2016) Nature communications 7, 10953. PMID: 27218149 | ||||||||
| Note | For research use only |

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