

| 货号 | HB522014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-DCAF15 Polyclonal Antibody (HB522014) is a rabbit polyclonal antibody detecting DDB1- and CUL4-associated factor 15; DCAF15; C19orf72 in ELISA, IHC, WB. Suitable for Human, Bovine, Mouse, and Frog.
Highlights
| ||||||||
| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human DCAF15 (Tyr386-Val564). | ||||||||
| 靶标 | DDB1- and CUL4-associated factor 15; DCAF15; C19orf72 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q66K64, Q3SZD5, Q6PFH3, A2BDA5 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||||
| 产品使用信息 |
| ||||||||
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | DDB1- and CUL4-associated factor 15 (DCAF15) is a ~66 kDa protein. Substrate-recognition component of the DCX(DCAF15) complex, a cullin-4-RING E3 ubiquitin-protein ligase complex that mediates ubiquitination and degradation of target proteins. The DCX(DCAF15) complex acts as a regulator of the natural killer (NK) cells effector functions, possibly by mediating ubiquitination and degradation of cohesin subunits SMC1A and SMC3. May play a role in the activation of antigen-presenting cells (APC) and their interaction with NK cells. 1. Jin, J. et al. (2006) Molecular cell 23, 709-21. PMID: 16949367 2. Pech, MF. et al. (2019) eLife 8. PMID: 31452512 | ||||||||
| Note | For research use only |

24小时产品查询

扫一扫关注我们

专属渠道经理