Anti-USP48 Polyclonal Antibody (HB559014)

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概述
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参考文献
产品说明书

概述

货号

HB559014

品牌

abinScience

描述

Anti-USP48 Polyclonal Antibody (HB559014) is a rabbit polyclonal antibody detecting Ubiquitin carboxyl-terminal hydrolase 48; 3.4.19.12; Deubiquitinating enzyme 48; Ubiquitin thioesterase 48; Ubiquitin-specific peptidase 48; Ubiquitin-specific protease 48; Ubiquitin-specific-processing protease 48; USP48; USP31 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Chicken.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human USP48 (Thr97-Thr422).

靶标

Ubiquitin carboxyl-terminal hydrolase 48; 3.4.19.12; Deubiquitinating enzyme 48; Ubiquitin thioesterase 48; Ubiquitin-specific peptidase 48; Ubiquitin-specific protease 48; Ubiquitin-specific-processing protease 48; USP48; USP31

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q86UV5, Q3V0C5, Q76LT8, Q5ZM45

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Ubiquitin carboxyl-terminal hydrolase 48 (USP48) is a ~119 kDa protein. Deubiquitinase that recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of polyubiquitin precursors as well as that of ubiquitinated proteins. Plays a role in the regulation of NF-kappa-B activation by TNF receptor superfamily via its interactions with RELA and TRAF2. May also play a regulatory role at postsynaptic sites. Plays an important role in cell cycle progression by deubiquitinating Aurora B/AURKB and thereby extending its stability.

1. Tzimas, C. et al. (2006) Cellular signalling 18, 83-92. PMID: 16214042

2. Bassani, S. et al. (2021) Human molecular genetics 30, 1785-1796. PMID: 34059922

3. Antao, AM. et al. (2021) International journal of molecular sciences 22. PMID: 34445214

4. Jantaree, P. et al. (2022) Cellular and molecular life sciences : CMLS 79, 461. PMID: 35913642

5. Sánchez-Bellver, L. et al. (2022) International journal of molecular sciences 23. PMID: 36293380

6. Ren, Y. et al. (2023) Cancer research 83, 1074-1093. PMID: 36607699

Note

For research use only

图片

参考文献

产品说明书

Anti-USP48 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-USP48 Polyclonal Antibody (HB559014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-USP48 Polyclonal Antibody (HB559014)

概述

图片

参考文献

产品说明书

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