Anti-SEC16A Polyclonal Antibody (HB575014)

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50ug
100ug

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概述
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参考文献
产品说明书

概述

货号

HB575014

品牌

abinScience

描述

Anti-SEC16A Polyclonal Antibody (HB575014) is a rabbit polyclonal antibody detecting Protein transport protein Sec16A; SEC16 homolog A; p250; SEC16A; KIAA0310; SEC16; SEC16L in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human SEC16A (Ser1612-Gly1890).

靶标

Protein transport protein Sec16A; SEC16 homolog A; p250; SEC16A; KIAA0310; SEC16; SEC16L

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

O15027, E9QAT4

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Protein transport protein Sec16A is a ~251 kDa protein. Acts as a molecular scaffold that plays a key role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining an ERES. Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Mediates the recruitment of MIA3/TANGO to ERES. Regulates both conventional (ER/Golgi-dependent) and GORASP2-mediated unconventional (ER/Golgi-independent) trafficking of CFTR to cell membrane.

1. Watson, P. et al. (2006) Traffic (Copenhagen, Denmark) 7, 1678-87. PMID: 17005010

2. Bhattacharyya, D. et al. (2007) Molecular biology of the cell 18, 839-49. PMID: 17192411

3. Iinuma, T. et al. (2007) The Journal of biological chemistry 282, 17632-9. PMID: 17428803

4. Yonekawa, S. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 12746-51. PMID: 21768384

5. Budnik, A. et al. (2011) Scientific reports 1, 77. PMID: 22355596

6. Maeda, M. et al. (2017) The Journal of cell biology 216, 1731-1743. PMID: 28442536

7. Piao, H. et al. (2017) Scientific reports 7, 39887. PMID: 28067262

8. Wu, Y. et al. (2018) PloS one 13, e0190407. PMID: 29300766

Note

For research use only

图片

参考文献

产品说明书

Anti-SEC16A Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-SEC16A Polyclonal Antibody (HB575014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-SEC16A Polyclonal Antibody (HB575014)

概述

图片

参考文献

产品说明书

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