

| 货号 | HB590014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-GPR137B Polyclonal Antibody (HB590014) is a rabbit polyclonal antibody detecting Integral membrane protein GPR137B; Transmembrane 7 superfamily member 1 protein; GPR137B; TM7SF1 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human GPR137B (Val315-Gly399). | ||||||||
| 靶标 | Integral membrane protein GPR137B; Transmembrane 7 superfamily member 1 protein; GPR137B; TM7SF1 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | O60478, Q8BNQ3 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Integral membrane protein GPR137B is a ~45 kDa protein. Lysosomal integral membrane protein that regulates the localization and activity of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Interacts with Rag GTPases and increases the lysosomial localization and activity of Rag GTPases and thereby regulates mTORC1 translocation and activity in lysosome. Involved in the regulation of lysosomal morphology and autophagy. 1. Gan, L. et al. (2019) Nature cell biology 21, 614-626. PMID: 31036939 | ||||||||
| Note | For research use only |

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