Anti-CORO1C Polyclonal Antibody (HB597014)

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50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HB597014

品牌

abinScience

描述

Anti-CORO1C Polyclonal Antibody (HB597014) is a rabbit polyclonal antibody detecting Coronin-1C; Coronin-3; hCRNN4; CORO1C; CRN2; CRNN4 in ELISA, IHC, WB. Suitable for Human, Mouse, and Zebrafish.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human CORO1C (Met1-Arg352).

靶标

Coronin-1C; Coronin-3; hCRNN4; CORO1C; CRN2; CRNN4

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q9ULV4, Q9WUM4, B0R0D7

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Coronin-1C (CORO1C) is a ~53 kDa protein. Plays a role in directed cell migration by regulating the activation and subcellular location of RAC1. Increases the presence of activated RAC1 at the leading edge of migrating cells. Required for normal organization of the cytoskeleton, including the actin cytoskeleton, microtubules and the vimentin intermediate filaments. Plays a role in endoplasmic reticulum-associated endosome fission: localizes to endosome membrane tubules and promotes recruitment of TMCC1, leading to recruitment of the endoplasmic reticulum to endosome tubules for fission. Endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane.

1. Williamson, RC. et al. (2014) Journal of cell science 127, 4292-307. PMID: 25074804

2. Williamson, RC. et al. (2015) The Journal of biological chemistry 290, 15437-15449. PMID: 25925950

3. Hoyer, MJ. et al. (2018) Cell 175, 254-265.e14. PMID: 30220460

Note

For research use only

图片

参考文献

产品说明书

Anti-CORO1C Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CORO1C Polyclonal Antibody (HB597014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-CORO1C Polyclonal Antibody (HB597014)

概述

图片

参考文献

产品说明书

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