

| 货号 | HA916014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-ARL6 Polyclonal Antibody (HA916014) is a rabbit polyclonal antibody detecting ADP-ribosylation factor-like protein 6; Bardet-Biedl syndrome 3 protein; ARL6; BBS3 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Zebrafish.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human ARL6 (Met1-Thr186). | ||||||||
| 靶标 | ADP-ribosylation factor-like protein 6; Bardet-Biedl syndrome 3 protein; ARL6; BBS3 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q9H0F7, O88848, Q0IIM2, Q5M9P8 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | ADP-ribosylation factor-like protein 6 (ARL6) is a ~21 kDa protein. Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia. Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia. Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade. 1. Jin, H. et al. (2010) Cell 141, 1208-19. PMID: 20603001 2. Seo, S. et al. (2011) PLoS genetics 7, e1002358. PMID: 22072986 3. Wiens, CJ. et al. (2010) The Journal of biological chemistry 285, 16218-30. PMID: 20207729 | ||||||||
| Note | For research use only |

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