Anti-XPO4 Polyclonal Antibody (HC006014)

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50ug
100ug

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概述
图片
参考文献
产品说明书

概述

货号

HC006014

品牌

abinScience

描述

Anti-XPO4 Polyclonal Antibody (HC006014) is a rabbit polyclonal antibody in ELISA, IHC, WB. Suitable for Human, Chicken, Mouse, Frog, and Zebrafish.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant human XPO4 (Met28-Asn256).

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q9C0E2, Q5ZMR9, Q9ESJ0, Q499Y0, Q802D3

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Exportin-4 (XPO4) is a ~130 kDa protein. Mediates the nuclear export of proteins (cargos), such as EIF5A, SMAD3 and isoform M2 of PKM (PKM2). In the nucleus binds cooperatively to its cargo and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the cargo from the export receptor. XPO4 then return to the nuclear compartment and mediate another round of transport.

1. Lipowsky, G. et al. (2000) The EMBO journal 19, 4362-71. PMID: 10944119

2. Kurisaki, A. et al. (2006) Molecular and cellular biology 26, 1318-32. PMID: 16449645

3. Bhardwaj, A. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, E538-47. PMID: 26787900

Note

For research use only

图片

参考文献

产品说明书

Anti-XPO4 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-XPO4 Polyclonal Antibody (HC006014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-XPO4 Polyclonal Antibody (HC006014)

概述

图片

参考文献

产品说明书

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