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Anti-AP4M1 Polyclonal Antibody (HC009014)

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概述
货号HC009014
品牌abinScience
描述
Anti-AP4M1 Polyclonal Antibody (HC009014) is a rabbit polyclonal antibody detecting AP-4 complex subunit mu-1; AP-4 adaptor complex mu subunit; Adaptor-related protein complex 4 subunit mu-1; Mu subunit of AP-4; Mu-adaptin-related protein 2; mu-ARP2; Mu4-adaptin; mu4; AP4M1; MUARP2 in ELISA, IHC, WB. Suitable for Human, Bovine, Dog, Rat, and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant human AP4M1 (Lys184-Ile453).
靶标AP-4 complex subunit mu-1; AP-4 adaptor complex mu subunit; Adaptor-related protein complex 4 subunit mu-1; Mu subunit of AP-4; Mu-adaptin-related protein 2; mu-ARP2; Mu4-adaptin; mu4; AP4M1; MUARP2
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号O00189, Q29RY8, E2RED8, Q2PWT8, Q9JKC7
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

AP-4 complex subunit mu-1 (AP4M1) is a ~49 kDa protein. Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons.

1. Dell'Angelica, EC. et al. (1999) The Journal of biological chemistry 274, 7278-85. PMID: 10066790
2. Hirst, J. et al. (1999) Molecular biology of the cell 10, 2787-802. PMID: 10436028
3. Aguilar, RC. et al. (2001) The Journal of biological chemistry 276, 13145-52. PMID: 11139587
4. Simmen, T. et al. (2002) Nature cell biology 4, 154-9. PMID: 11802162
5. Burgos, PV. et al. (2010) Developmental cell 18, 425-36. PMID: 20230749
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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