

| 货号 | HY063024 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-HMOX1 Polyclonal Antibody (HY063024) is a rabbit polyclonal antibody detecting HMOX1 in ELISA, IHC, WB. Suitable for Human, Bovine, and Pig.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human HMOX1 (Gln11-Ser229). | ||||||||
| 靶标 | Heme oxygenase 1, HO-1, EC:1.14.14.18, Heme oxygenase 1 soluble form, HMOX1, HO, HO1 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 观测分子量 | ~30 kDa | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P09601, P14901 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Heme oxygenase 1 (HMOX1) is a ~32 kDa protein. Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. Affords protection against programmed cell death and this cytoprotective effect relies on its ability to catabolize free heme and prevent it from sensitizing cells to undergo apoptosis. 1. Lightning, LK. et al. (2001) The Journal of biological chemistry 276, 10612-9. PMID: 11121422 2. Hwang, HW. et al. (2009) The Journal of biological chemistry 284, 22672-9. PMID: 19556236 3. Wilks, A. et al. (1995) Biochemistry 34, 4421-7. PMID: 7703255 4. Gozzelino, R. et al. (2010) Annual review of pharmacology and toxicology 50, 323-54. PMID: 20055707 | ||||||||
| Note | For research use only |

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