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Anti-HMOX1 Polyclonal Antibody (HY063024)

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概述
货号HY063024
品牌abinScience
描述
Anti-HMOX1 Polyclonal Antibody (HY063024) is a rabbit polyclonal antibody detecting HMOX1 in ELISA, IHC, WB. Suitable for Human, Bovine, and Pig.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant human HMOX1 (Gln11-Ser229).
靶标Heme oxygenase 1, HO-1, EC:1.14.14.18, Heme oxygenase 1 soluble form, HMOX1, HO, HO1
内毒素水平Please contact with the lab for this information.
观测分子量~30 kDa
纯化方式Purified by antigen affinity column.
Accession号P09601, P14901
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Heme oxygenase 1 (HMOX1) is a ~32 kDa protein. Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron. Affords protection against programmed cell death and this cytoprotective effect relies on its ability to catabolize free heme and prevent it from sensitizing cells to undergo apoptosis.

1. Lightning, LK. et al. (2001) The Journal of biological chemistry 276, 10612-9. PMID: 11121422
2. Hwang, HW. et al. (2009) The Journal of biological chemistry 284, 22672-9. PMID: 19556236
3. Wilks, A. et al. (1995) Biochemistry 34, 4421-7. PMID: 7703255
4. Gozzelino, R. et al. (2010) Annual review of pharmacology and toxicology 50, 323-54. PMID: 20055707
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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