Anti-Mouse SPNS2 Polyclonal Antibody (MA888014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

MA888014

品牌

abinScience

描述

Anti-Mouse SPNS2 Polyclonal Antibody (MA888014) is a rabbit polyclonal antibody detecting Sphingosine-1-phosphate transporter SPNS2; Protein spinster homolog 2; Spinster homolog 2; Spns2; Spns2 in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant mouse SPNS2 (Met2-Ala140).

靶标

Sphingosine-1-phosphate transporter SPNS2; Protein spinster homolog 2; Spinster homolog 2; Spns2; Spns2

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q91VM4

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Sphingosine-1-phosphate transporter SPNS2 is a ~58 kDa protein. Lipid transporter that specifically mediates export of sphingosine-1-phosphate (sphing-4-enine 1-phosphate, S1P) and sphinganine-1-phosphate in the lymph, thereby playing a role in lymphocyte trafficking. S1P is a bioactive signaling molecule that regulates many physiological processes important for the development and for the immune system. Regulates levels of S1P and the S1P gradient that exists between the high circulating concentrations of S1P and low tissue levels that control lymphocyte trafficking. Required for the egress of T-cells from lymph nodes during an immune response by mediating S1P secretion, which generates a gradient that enables activated T-cells to access lymph. Also required for the egress of immature B-cells from the bone marrow.

1. Fukuhara, S. et al. (2012) The Journal of clinical investigation 122, 1416-26. PMID: 22406534

2. Nijnik, A. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 102-11. PMID: 22664872

3. Mendoza, A. et al. (2012) Cell reports 2, 1104-10. PMID: 23103166

4. Nagahashi, M. et al. (2013) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 27, 1001-11. PMID: 23180825

5. Okuniewska, M. et al. (2021) Cell reports 36, 109368. PMID: 34260944

Note

For research use only

图片

参考文献

产品说明书

Anti-Mouse SPNS2 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse SPNS2 Polyclonal Antibody (MA888014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse SPNS2 Polyclonal Antibody (MA888014)

概述

图片

参考文献

产品说明书

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