

| 货号 | MC071014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-PLIN5 Polyclonal Antibody (MC071014) is a rabbit polyclonal antibody detecting Perilipin-5; Lipid droplet-associated protein PAT-1; Lipid storage droplet protein 5; Myocardial LD protein; Plin5; Lsdp5; Mldp; Oxpat; Pat1 in ELISA, IHC, WB. Suitable for Rat and Mouse.
Highlights
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| 种属反应性 | Mouse | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant mouse PLIN5 (Asp178-Leu397). | ||||||||
| 靶标 | Perilipin-5; Lipid droplet-associated protein PAT-1; Lipid storage droplet protein 5; Myocardial LD protein; Plin5; Lsdp5; Mldp; Oxpat; Pat1 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | M0R7Z9, Q8BVZ1 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Perilipin-5 (PLIN5) is a ~51 kDa protein. Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. | ||||||||
| Note | For research use only |

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