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Anti-SERPINI1 Polyclonal Antibody (MC075014)

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规格:
  • 50ug
  • 100ug
数量:
  • 概述

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  • 参考文献

  • 产品说明书

概述
货号MC075014
品牌abinScience
描述
Anti-SERPINI1 Polyclonal Antibody (MC075014) is a rabbit polyclonal antibody detecting Neuroserpin; Peptidase inhibitor 12; PI-12; Serine protease inhibitor 17; Serpin I1; Serpini1; Pi12; Spi17 in ELISA, IHC, WB. Suitable for Mouse, Human, and Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
种属反应性Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant mouse SERPINI1 (Thr17-Leu410).
靶标Neuroserpin; Peptidase inhibitor 12; PI-12; Serine protease inhibitor 17; Serpin I1; Serpini1; Pi12; Spi17
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q99574, O35684, Q9JLD2
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Neuroserpin (SERPINI1) is a ~46 kDa protein. Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator (Probable).

1. Belorgey, D. et al. (2002) The Journal of biological chemistry 277, 17367-73. PMID: 11880376
2. Ricagno, S. et al. (2009) Journal of molecular biology 388, 109-21. PMID: 19265707
3. Takehara, S. et al. (2009) Journal of molecular biology 388, 11-20. PMID: 19285087
4. Noto, R. et al. (2015) Scientific reports 5, 13666. PMID: 26329378
5. Osterwalder, T. et al. (1998) The Journal of biological chemistry 273, 2312-21. PMID: 9442076
NoteFor research use only
图片
  • Western blot

    Western blot analysis was performed using anti-SERPINI1 polyclonal antibody at 1ug/mL on various samples.
    Lane 1: K562 cell lysate

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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