Anti-P2RX7 Polyclonal Antibody (MV713014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

MV713014

品牌

abinScience

描述

Anti-P2RX7 Polyclonal Antibody (MV713014) is a rabbit polyclonal antibody detecting P2X purinoceptor 7; P2X7; ATP receptor; P2Z receptor; Purinergic receptor; P2rx7; P2x7 in ELISA, IHC, WB. Suitable for Rat and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant mouse P2RX7 (Gln52-Asp329).

靶标

P2X purinoceptor 7; P2X7; ATP receptor; P2Z receptor; Purinergic receptor; P2rx7; P2x7

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q9Z1M0, Q64663

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

P2X purinoceptor 7 (P2RX7) is a ~68 kDa protein. ATP-gated nonselective transmembrane cation channel. Requires high millimolar-range concentrations of ATP to become activated. ATP binding trigers the rapid opening of the channel and allows Na(+) and Ca(2+) influx and K(+) efflux. Has also the ability to form a large pore in the cell membrane, allowing the passage of large cationic molecules. In microglia, may mediate NADPH transport across the plasma membrane.

1. Chessell, IP. et al. (1998) FEBS letters 439, 26-30. PMID: 9849870

2. Robinson, LE. et al. (2014) The Journal of biological chemistry 289, 31983-31994. PMID: 25281740

3. Karmakar, M. et al. (2016) Nature communications 7, 10555. PMID: 26877061

4. Di, A. et al. (2018) Immunity 49, 56-65.e4. PMID: 29958799

5. Yang, D. et al. (2015) Immunity 43, 923-32. PMID: 26572062

Note

For research use only

图片

参考文献

产品说明书

Anti-P2RX7 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-P2RX7 Polyclonal Antibody (MV713014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-P2RX7 Polyclonal Antibody (MV713014)

概述

图片

参考文献

产品说明书

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