Anti-MUC2 Polyclonal Antibody (MX889014)

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50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

MX889014

品牌

abinScience

描述

Anti-MUC2 Polyclonal Antibody (MX889014) is a rabbit polyclonal antibody detecting Mucin-2; MUC-2; Colonic mucin; MCM; Secreted gel-forming mucin; Muc2 in ELISA, IHC, WB. Suitable for Mouse and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant mouse MUC2 (Asn31-His350).

靶标

Mucin-2; MUC-2; Colonic mucin; MCM; Secreted gel-forming mucin; Muc2

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q80Z19, Q62635

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Mucin-2 (MUC2) is a ~479 kDa protein. Coats the epithelia of the intestines and other mucus membrane-containing organs to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of the colon mucus, which is mainly formed by large polymeric networks of MUC2 secreted by goblet cells that cover the exposed surfaces of intestine. MUC2 networks form hydrogels that guard the underlying epithelium from pathogens and other hazardous matter entering from the outside world, while permitting nutrient absorption and gas exchange. Acts as a divalent copper chaperone that protects intestinal cells from copper toxicity and facilitates nutritional copper unptake into cells. Binds both Cu(2+) and its reduced form, Cu(1+), at two juxtaposed binding sites: Cu(2+), once reduced to Cu(1+) by vitamin C (ascorbate) or other dietary antioxidants, transits to the other binding site.

1. Johansson, ME. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 15064-9. PMID: 18806221

2. Johansson, ME. et al. (2009) Journal of proteome research 8, 3549-57. PMID: 19432394

3. Bergstrom, K. et al. (2020) Science (New York, N.Y.) 370, 467-472. PMID: 33093110

Note

For research use only

图片

参考文献

产品说明书

Anti-MUC2 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-MUC2 Polyclonal Antibody (MX889014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-MUC2 Polyclonal Antibody (MX889014)

概述

图片

参考文献

产品说明书

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