InVivoMAb Anti-Mouse IL-6 Antibody (MP5-20F3) (MY328020)

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规格：

100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

概述

货号

MY328020

品牌

abinScience

描述

InVivoMAb Anti-Mouse IL6 (MP5-20F3) [MP5-20F3] (MY328020) is a rat monoclonal antibody detecting Interleukin-6 in ELISA, FACS, Functional assay, Research in vivo. Suitable for Mouse.

Highlights

●Multi-Application — Validated across multiple applications.

种属反应性

Mouse

应用

in vivo IL-6 neutralization, in vitro IL-10 neutralization

宿主

Rat

克隆类型

Monoclonal

同种型

IgG1, kappa

克隆号

MP5-20F3

靶标

Interleukin-6, IL-6, B-cell stimulatory factor 2, BSF-2, CTL differentiation factor, CDF, Hybridoma growth factor, Interferon beta-2, IFN-beta-2, IL6, IFNB2

内毒素水平

< 1 EU/mg as determined by LAL method.

纯度

>95% as determined by SDS-PAGE.

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

P08505

状态

Liquid

保存溶液

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Interleukin-6 (IL6) is a ~23 kDa protein. Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable). IL6 is the therapeutic target of tocilizumab (Actemra).

Note

For research use only

Isotype Control

Rat IgG1, kappa Recombinant Isotype Control Antibody (RTK2071) (RV080407)

图片

SDS-PAGE

SDS-PAGE for InVivoMAb Anti-Mouse IL-6 Antibody (MP5-20F3)

参考文献

产品说明书

InVivoMAb Anti-Mouse IL-6 Antibody (MP5-20F3).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Mouse IL-6 Antibody (MP5-20F3) (MY328020)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Mouse IL-6 Antibody (MP5-20F3) (MY328020)

概述

图片

参考文献

产品说明书

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