InVivoMAb Anti-Mouse IL-6R alpha/IL6R Antibody (15A7) (MY583010)

价格:

规格：

100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

概述

货号

MY583010

品牌

abinScience

描述

InVivoMAb Anti-Mouse IL6R (15A7) [15A7] (MY583010) is a rat monoclonal antibody detecting Interleukin-6 receptor subunit alpha in ELISA, FACS, Functional assay, Research in vivo. Suitable for Mouse.

Highlights

●Multi-Application — Validated across multiple applications.

种属反应性

Mouse

应用

ELISA, FACS, Functional assay, Research in vivo

宿主

Rat

同种型

IgG2b, kappa

克隆号

15A7

克隆类型

Monoclonal

靶标

Interleukin-6 receptor subunit alpha, IL-6 receptor subunit alpha, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL-6R 1, Membrane glycoprotein 80, gp80, CD126, Soluble interleukin-6 receptor subunit alpha, sIL6R, IL6R

内毒素水平

< 10 EU/mg

纯度

>95% as determined by SDS-PAGE.

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

P08887

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Interleukin-6 receptor subunit alpha (IL6R) is a ~51 kDa protein. Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response, acute-phase reactions and hematopoiesis. The interaction with membrane-bound IL6R and IL6ST stimulates 'classic signaling', the restricted expression of the IL6R limits classic IL6 signaling to only a few tissues such as the liver and some cells of the immune system.

1. Larsen, JV. et al. (2017) Molecular and cellular biology 37. PMID: 28265003

2. Kang, S. et al. (2019) Immunity 50, 1007-1023. PMID: 30995492

3. Spencer, S. et al. (2019) The Journal of experimental medicine 216, 1986-1998. PMID: 31235509

Note

For research use only.

图片

SDS-PAGE

SDS-PAGE for InVivoMAb Anti-Mouse IL6R (15A7)

参考文献

产品说明书

InVivoMAb Anti-Mouse IL-6R alpha/IL6R Antibody (15A7).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Mouse IL-6R alpha/IL6R Antibody (15A7) (MY583010)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

InVivoMAb Anti-Mouse IL-6R alpha/IL6R Antibody (15A7) (MY583010)

概述

图片

参考文献

产品说明书

相关产品推荐

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