Anti-Human SLC15A4 Recombinant Antibody (SAA2355) (HC091013)

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规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HC091013

abinScience

种属反应性

Human

ELISA

Mouse

Monoclonal

SAA2355

Solute carrier family 15 member 4, Peptide transporter 4, Peptide/histidine transporter 1, hPHT1, SLC15A4, PHT1, PTR4

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q8N697

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Solute carrier family 15 member 4 (SLC15A4) is a ~62 kDa protein. Proton-coupled amino-acid transporter that mediates the transmembrane transport of L-histidine and some di- and tripeptides from inside the lysosome to the cytosol, and plays a key role in innate immune response. Preferably binds to short peptides with a basic residue at the first position and a hydrophobic residue at the second position. Able to transport a variety of di- and tripeptides, including carnosine and some peptidoglycans. Transporter activity is pH-dependent and maximized in the acidic lysosomal environment. Involved in the detection of microbial pathogens by toll-like receptors (TLRs) and NOD-like receptors (NLRs), probably by mediating transport of bacterial peptidoglycans across the endolysosomal membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand, and L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate (tri-DAP), the NOD1 ligand.

1. Bhardwaj, RK. et al. (2006) European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 27, 533-42. PMID: 16289537

2. Kobayashi, T. et al. (2014) Immunity 41, 375-388. PMID: 25238095

3. Song, F. et al. (2018) Molecular pharmaceutics 15, 385-393. PMID: 29224352

4. Zhang, Z. et al. (2025) Structure (London, England : 1993) 33, 330-337.e4. PMID: 39719710

5. Oppermann, H. et al. (2019) Amino acids 51, 999-1008. PMID: 31073693

6. Heinz, LX. et al. (2020) Nature 581, 316-322. PMID: 32433612

For research use only

SDS-PAGE

SDS-PAGE for Anti-Human SLC15A4 Antibody (SAA2355)

产品说明书

Anti-Human SLC15A4 Recombinant Antibody (SAA2355).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SLC15A4 Recombinant Antibody (SAA2355) (HC091013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SLC15A4 Recombinant Antibody (SAA2355) (HC091013)

概述

图片

参考文献

产品说明书

相关产品推荐

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