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Anti-MERS-CoV ORF4b Polyclonal Antibody (VK073034)

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概述
货号VK073034
品牌abinScience
描述
Anti-MERS-CoV ORF4b Polyclonal Antibody (VK073034) is a rabbit polyclonal antibody detecting Non-structural protein ORF4b; ORF4b; ORF4b in ELISA, IHC, WB.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Middle East respiratory syndrome-related coronavirus (MERS-CoV)
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant mers-cov ORF4b (Met1-Phe246(Pro44His)).
靶标Non-structural protein ORF4b; ORF4b; ORF4b
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号K9N643
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Non-structural protein ORF4b is a ~28 kDa protein. Plays a role in the inhibition of host innate immunity by inhibiting the interaction between host IKBKE and MAVS. In turn, this inhibition prevents the production of host interferon beta. Additionally, inhibits host NF-kappa-B by interacting with host KPNA4 and thereby preventing the translocation of the NF-kappa-B complex into the nucleus by this importin.

1. Canton, J. et al. (2018) PLoS pathogens 14, e1006838. PMID: 29370303
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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