Anti-EBV/HHV4 BMRF1 Polyclonal Antibody (VK074014)

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100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

VK074014

品牌

abinScience

描述

Anti-EBV/HHV4 BMRF1 Polyclonal Antibody (VK074014) is a rabbit polyclonal antibody detecting DNA polymerase processivity factor BMRF1 in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Epstein-Barr virus (HHV-4) (Human herpesvirus 4)

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant EBV/HHV4 BMRF1 (Met1-Ser314).

靶标

DNA polymerase processivity factor BMRF1, Early Antigen Diffused, EA-D, Polymerase accessory subunit

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P03191

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

DNA polymerase processivity factor BMRF1 is a ~43 kDa protein. Acts as a DNA polymerase processivity factor; a transcriptional activator for several EBV promoters and inhibits the host DNA damage response (DDR) to double-stranded DNA breaks. Plays an essential role in the viral lytic DNA replication by acting as a polymerase accessory subunit. Stimulates the viral DNA polymerase activity and appears to function with it as a holoenzyme. Increases the processivity of the viral polymerase, probably by acting as a sliding clamp that prevents dissociation of the polymerase from the active template. In addition, BMRF1 transcriptionally activates the oriLyt early BHLF1 promoter.

1. Neuhierl, B. et al. (2006) Journal of virology 80, 5078-81. PMID: 16641300

2. Murayama, K. et al. (2009) The Journal of biological chemistry 284, 35896-905. PMID: 19801550

3. Salamun, SG. et al. (2019) Journal of virology 93. PMID: 31462557

4. Zhang, Q. et al. (1996) Journal of virology 70, 5131-42. PMID: 8764021

5. Zhang, Q. et al. (1997) Virology 230, 22-34. PMID: 9126259

Note

For research use only

图片

参考文献

产品说明书

Anti-EBV/HHV4 BMRF1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-EBV/HHV4 BMRF1 Polyclonal Antibody (VK074014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-EBV/HHV4 BMRF1 Polyclonal Antibody (VK074014)

概述

图片

参考文献

产品说明书

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