

| 货号 | VK079014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-VP2 Polyclonal Antibody (VK079014) is a rabbit polyclonal antibody detecting 1B VP2 mature peptide; 1B VP2 mature peptide in ELISA, IHC, WB.
Highlights
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| 种属反应性 | Hepatitis A virus (HAV) | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant hav VP2 (Asp1-Gln222). | ||||||||
| 靶标 | 1B VP2 mature peptide; 1B VP2 mature peptide | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P08617, Q67825, Q9DWR1, Q02381, P31788, Q05794, P13901, P06442, A5LGW7, P14553, Q5Y944, Q8V0N6, A3FMB2, P06441 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Genome polyprotein (VP2) is a ~251 kDa protein. Capsid proteins VP1, VP2, and VP3 form a closed capsid enclosing the viral positive strand RNA genome. All these proteins contain a beta-sheet structure called beta-barrel jelly roll. Together they form an icosahedral capsid (T=3) composed of 60 copies of each VP1, VP2, and VP3, with a diameter of approximately 300 Angstroms. VP1 is situated at the 12 fivefold axes, whereas VP2 and VP3 are located at the quasi-sixfold axes. The naked capsid interacts with the host receptor HAVCR1 to provide virion attachment to and probably entry into the target cell. 1. Wang, X. et al. (2015) Nature 517, 85-88. PMID: 25327248 2. Wang, X. et al. (2017) Proceedings of the National Academy of Sciences of the United States of America 114, 770-775. PMID: 28074040 3. Silberstein, E. et al. (2001) Journal of virology 75, 717-25. PMID: 11134285 4. Costafreda, MI. et al. (2018) Journal of virology 92. PMID: 29437974 5. Feigelstock, D. et al. (1998) Journal of virology 72, 6621-8. PMID: 9658108 | ||||||||
| Note | For research use only |

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