

| 货号 | VK658014 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 描述 |
Anti-HPV16 L2 Polyclonal Antibody (VK658014) is a rabbit polyclonal antibody detecting HPV16 L2 in ELISA, IHC, WB.
Highlights
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| 种属反应性 | Human papillomavirus 16 (HPV16) | ||||
| 应用 | ELISA, IHC, WB | ||||
| 宿主 | Rabbit | ||||
| 同种型 | IgG | ||||
| 克隆类型 | Polyclonal | ||||
| 免疫原 | E. coli - derived recombinant HPV16 L2 (Arg2-Ala473(Glu43Asp)). | ||||
| 靶标 | Minor capsid protein L2, L2 | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯化方式 | Purified by antigen affinity column. | ||||
| Accession号 | P03107 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Minor capsid protein L2 is a ~50 kDa protein. Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers. Plays a role in capsid stabilization through interaction with the major capsid protein L1. Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network. Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network. Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus. | ||||
| Note | For research use only |

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