

| 货号 | VK556054 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 描述 |
Anti-HPV31 E7 Polyclonal Antibody (VK556054) is a rabbit polyclonal antibody detecting Protein E7 in ELISA, IHC, WB.
Highlights
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| 种属反应性 | Human papillomavirus 31 (HPV31) | ||||
| 应用 | ELISA, IHC, WB | ||||
| 宿主 | Rabbit | ||||
| 同种型 | IgG | ||||
| 克隆类型 | Polyclonal | ||||
| 免疫原 | E. coli - derived recombinant HPV31 E7 (Met1-Leu98). | ||||
| 靶标 | Protein E7, E7 | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯化方式 | Purified by antigen affinity column. | ||||
| Accession号 | P17387 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Protein E7 is a ~10 kDa protein. E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. | ||||
| Note | For research use only |

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