

| 货号 | VK093014 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 描述 |
Anti-MRV-1 SigmaNS/S3 Polyclonal Antibody (VK093014) is a rabbit polyclonal antibody detecting MRV-1 SigmaNS/S3 in ELISA, IHC, WB. Suitable for Reovirus type 1, Reovirus type 2, and Reovirus type 3.
Highlights
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| 种属反应性 | Mammalian orthoreovirus 1 (MRV1) | ||||
| 应用 | ELISA, IHC, WB | ||||
| 宿主 | Rabbit | ||||
| 克隆类型 | Polyclonal | ||||
| 同种型 | IgG | ||||
| 免疫原 | E. coli - derived recombinant MRV-1 SigmaNS/S3 (Met1-Val366). | ||||
| 靶标 | sigma-NS protein, S3 | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯化方式 | Purified by antigen affinity column. | ||||
| Accession号 | P07940, P12002, P03526 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Protein sigma-NS (SigmaNS/S3) is a ~41 kDa protein. Protein that binds to ssRNA and participates with protein mu-NS in forming the matrix of viral factories, which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place. Plays a role in the inhibition of the integrated stress response (ISR) to escape from host cell translational shutoff. Participates in the disruption of stress granules (SG) through its association with host G3BP1 and mu-NS. 1. Gillian, AL. et al. (1998) Virology 240, 1-11. PMID: 9448684 2. Choudhury, P. et al. (2017) Journal of virology 91. PMID: 28794026 | ||||
| Note | For research use only |

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