

| 货号 | VK094034 | ||||
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| 品牌 | abinScience | ||||
| 描述 |
Anti-MRV-3 Outer capsid protein mu-1 Polyclonal Antibody (VK094034) is a rabbit polyclonal antibody detecting MRV-3 Outer capsid protein mu-1 in ELISA, IHC, WB. Suitable for Reovirus type 1, Reovirus type 2, and Reovirus type 3.
Highlights
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| 种属反应性 | Mammalian orthoreovirus 1 (MRV1) | ||||
| 应用 | ELISA, IHC, WB | ||||
| 宿主 | Rabbit | ||||
| 克隆类型 | Polyclonal | ||||
| 同种型 | IgG | ||||
| 免疫原 | E. coli - derived recombinant MRV-3 Outer capsid protein mu-1 (Lys317-Ser500). | ||||
| 靶标 | M2 | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯化方式 | Purified by antigen affinity column. | ||||
| Accession号 | P11077, P11078, P12397 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Outer capsid protein mu-1 is a ~76 kDa protein. Major outer capsid protein involved in host cell membrane penetration. In the endocytic compartment, outer-capsid protein sigma-3 is removed by cathepsin proteases, which exposes the viral membrane-penetration protein mu-1. Both myristoylated peptides mu-1N and phi are released during infectious subvirion particles (ISVP) formation in the endosome. They associate with host membranes and mu-1N induces permeabilization and delivery of transcriptionally active viral particles into the host cell cytoplasm. Seems to induce apoptosis in the host cell. | ||||
| Note | For research use only |

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