首页 > 产品中心 > 抗体 > 一抗

Anti-MRV-3 Sigma1/S1 Polyclonal Antibody (VK094044)

价格:
规格:
  • 50ug
  • 100ug
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号VK094044
品牌abinScience
描述
Anti-MRV-3 Sigma1/S1 Polyclonal Antibody (VK094044) is a rabbit polyclonal antibody detecting MRV-3 Sigma1/S1 in ELISA, IHC, WB. Suitable for Bacillus phage SF6 and Reovirus type 3.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
种属反应性Mammalian orthoreovirus 1 (MRV1)
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant MRV-3 Sigma1/S1 (Val170-Thr455).
靶标sigma-1 protein, S1
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号P03528, P21270
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000,IHC:1:50-1:500,WB:1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Outer capsid protein sigma-1 (Sigma1/S1) is a ~49 kDa protein. Fiber-like molecule of about 30 nm that attaches the virion to the host cell membrane by binding with initial low affinity to sialic acid containing proteins, followed by high-affinity bindingto the entry receptor F11R/JAM-A. The interaction of sigma-1 with F11R is required for NF-kB activation and apoptosis. Binding to both sialic acid and F11R is required to induce maximal levels of apoptosis.

1. Barton, ES. et al. (2001) Cell 104, 441-51. PMID: 11239401
2. Kirchner, E. et al. (2008) PLoS pathogens 4, e1000235. PMID: 19079583
3. Reiter, DM. et al. (2011) PLoS pathogens 7, e1002166. PMID: 21829363
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐