

| 货号 | VK099014 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 描述 |
Anti-SV40 VP1 Polyclonal Antibody (VK099014) is a rabbit polyclonal antibody detecting Major structural protein VP1 in ELISA, IHC, WB. Suitable for Simian virus 40.
Highlights
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| 种属反应性 | Simian virus 40 (SV40) | ||||
| 应用 | ELISA, IHC, WB | ||||
| 宿主 | Rabbit | ||||
| 克隆类型 | Polyclonal | ||||
| 同种型 | IgG | ||||
| 免疫原 | E. coli - derived recombinant SV40 VP1 (Pro21-Gln362). | ||||
| 靶标 | Major capsid protein VP1, Major structural protein VP1 | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯化方式 | Purified by antigen affinity column. | ||||
| Accession号 | P03087 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Major capsid protein VP1 is a ~39 kDa protein. Forms an icosahedral capsid with a T=7 symmetry and a 40 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with VP2 or VP3 proteins. Binds to N-glycolylneuraminic analog of the ganglioside GM1 on the cell surface to provide virion attachment to target cell. Once attached, the virion is internalized by caveolin-mediated endocytosis and traffics to the endoplasmic reticulum. Inside the endoplasmic reticulum, the protein folding machinery isomerizes VP1 interpentamer disulfide bonds, thereby triggering initial uncoating. 1. Neu, U. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 5219-24. PMID: 18353982 2. Schelhaas, M. et al. (2007) Cell 131, 516-29. PMID: 17981119 | ||||
| Note | For research use only |

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