

| 货号 | VK101014 | ||||
|---|---|---|---|---|---|
| 品牌 | abinScience | ||||
| 描述 |
Anti-RVFV Glycoprotein N Polyclonal Antibody (VK101014) is a rabbit polyclonal antibody detecting glycoprotein in ELISA, IHC, WB.
Highlights
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| 种属反应性 | Rift valley fever virus (RVFV) | ||||
| 应用 | ELISA, IHC, WB | ||||
| 宿主 | Rabbit | ||||
| 克隆类型 | Polyclonal | ||||
| 同种型 | IgG | ||||
| 免疫原 | E. coli - derived recombinant RVFV Glycoprotein N (Glu154-Ser469). | ||||
| 靶标 | glycoprotein, glycoprotein | ||||
| 内毒素水平 | Please contact with the lab for this information. | ||||
| 纯化方式 | Purified by antigen affinity column. | ||||
| Accession号 | P21401, P03518 | ||||
| 状态 | Liquid | ||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 背景 | Envelopment polyprotein (Glycoprotein N) is a ~130 kDa protein. Structural component of the virion that interacts with glycoprotein C. It shields the hydrophobic fusion loops of the glycoprotein C, preventing premature fusion. The glycoprotein protrusions are arranged on an icosahedral lattice, with T=12 triangulation. They are able to attach the virion to the host cell receptor CD209/DC-SIGN and to promote fusion of membranes with the late endosome after endocytosis of the virion. Plays a role in the packaging of ribonucleoproteins and polymerase during virus assembly. 1. Freiberg, AN. et al. (2008) Journal of virology 82, 10341-8. PMID: 18715915 2. Halldorsson, S. et al. (2018) Nature communications 9, 349. PMID: 29367607 3. Lozach, PY. et al. (2011) Cell host & microbe 10, 75-88. PMID: 21767814 4. Piper, ME. et al. (2011) PloS one 6, e18070. PMID: 21445316 | ||||
| Note | For research use only |

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