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Anti-Human Calreticulin/CALR Monoclonal Antibody (1A460) (HB190105)

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概述
货号HB190105
品牌abinScience
描述
Anti-Human Calreticulin/CALR Monoclonal Antibody (1A460) [1A460] (HB190105) is a mouse monoclonal antibody detecting Calreticulin in FCM, WB. Suitable for Human.
Highlights
  • Flow Cytometry — Validated for flow cytometry applications.
种属反应性Human
应用FCM, WB
宿主Mouse
同种型IgG2a
克隆号1A460
克隆类型Monoclonal
靶标Calreticulin, CRP55, Calregulin, Endoplasmic reticulum resident protein 60, ERp60, HACBP, grp60, CALR, CRTC
内毒素水平Please contact with the lab for this information.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P27797
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Calreticulin is a ~48 kDa protein. Calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. This lectin interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Interacts with the DNA-binding domain of NR3C1 and mediates its nuclear export. Involved in maternal gene expression regulation. May participate in oocyte maturation via the regulation of calcium homeostasis.

1. Nauseef, WM. et al. (1995) The Journal of biological chemistry 270, 4741-7. PMID: 7876246
2. Holaska, JM. et al. (2001) The Journal of cell biology 152, 127-40. PMID: 11149926
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human Calreticulin/CALR Monoclonal Antibody (1A460)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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