Anti-Canine TNF-alpha Recombinant Nanobody (SAA2422) (CF879023)

价格:

规格：

50ug
100ug
1mg

数量：

联系我们

一键复制产品信息

概述
图片
参考文献
产品说明书

概述

货号

CF879023

品牌

abinScience

描述

Anti-Dog TNFa/TNF-alpha Nanobody (SAA2422) [SAA2422] (CF879023) is a alpaca monoclonal antibody detecting TNF-alpha in ELISA.

种属反应性

Canine

应用

ELISA

宿主

Alpaca

同种型

VHH-His

克隆号

SAA2422

克隆类型

Monoclonal

靶标

Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Tumor necrosis factor membrane form, N-terminal fragment, NTF, Intracellular domain 1, ICD1, Intracellular domain 2, ICD2, C-domain 1, C-domain 2, Tumor necrosis factor soluble form, TNF, TNFA, TNFSF2, TNFα

内毒素水平

Please contact with the lab for this information.

纯度

>95% as determined by SDS-PAGE.

纯化方式

Protein A/G purified from cell culture supernatant.

Accession号

P51742

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Tumor necrosis factor (TNFα) is a ~25 kDa protein. Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance.

Note

For research use only

图片

SDS-PAGE

SDS-PAGE for Anti-Dog TNFa/TNF-alpha Nanobody (SAA2422)

参考文献

产品说明书

Anti-Canine TNF-alpha Recombinant Nanobody (SAA2422).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Canine TNF-alpha Recombinant Nanobody (SAA2422) (CF879023)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Canine TNF-alpha Recombinant Nanobody (SAA2422) (CF879023)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价