

| 货号 | HA938014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-MFN1 Polyclonal Antibody (HA938014) is a rabbit polyclonal antibody detecting MFN1 in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.
Highlights
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| 种属反应性 | Human, Mouse, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant MFN1 (Met1-Gly298). | ||||||||
| 靶标 | EC:3.6.5.-, Fzo homolog, MFN1, Mitofusin-1, Transmembrane GTPase MFN1 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q8IWA4, Q8R4Z9, Q811U4 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Mitofusin-1 (MFN1) is a ~84 kDa protein. Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Membrane clustering requires GTPase activity. It may involve a major rearrangement of the coiled coil domains. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks (in vitro). 1. Legros, F. et al. (2002) Molecular biology of the cell 13, 4343-54. PMID: 12475957 2. Santel, A. et al. (2003) Journal of cell science 116, 2763-74. PMID: 12759376 3. Qi, Y. et al. (2016) The Journal of cell biology 215, 621-629. PMID: 27920125 4. Cao, YL. et al. (2017) Nature 542, 372-376. PMID: 28114303 | ||||||||
| Note | For research use only |

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